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SIRMIO related publications

Paper & Proceedings

2021

Tim Binder, Han Gyu Kang, Munetaka Nitta, Florian Schneider, Taiga Yamaya, Katia Parodi, Florian Wiest and Peter G. Thirolf; Performance evaluation of a staggered 3-layer DOI PET detector using a 1 mm LYSO pitch with PETsys TOFPET2 ASIC: Comparison of HAMAMATSU and KETEK SiPMs; accepted for publication in Phys. Med. Biol. (2021)

Julie Lascaud, Pratik Dash  Matthias Würl, Hans-Peter Wieser, Benjamin Wollant, Ronaldo Kalunga, Walter Assmann, Dirk-André Clevert, Alfredo Ferrari, Paola Sala, Alessandro Stuart Savoia and Katia Parodi; Enhancement of the ionoacoustic effect through ultrasound and photoacoustic contrast agents; Scientific Reports; 2021; https://doi.org/10.1038/s41598-021-81964-4

2020

Sonja Gerlach, Marco Pinto, Neeraj Kurichiyanil, Cai Grau, Joel Herault, Martin Hillbrand, Per Poulsen, Sairos Safai, Jacobus Maarten Schippers, Marco Schwarz, Christian Søndergaard, Francesco Tommasino, Enrico Verroi, Marie Vidal, Indra Yohannes, Jörg Schreiber, Katia Parodi; Beam characterization and feasibility study for a small animal irradiation platform at clinical proton therapy facilities; Phys. Med. Biol. 65 245045 (2020); https://epub.ub.uni-muenchen.de/74194/; https://doi.org/10.1088/1361-6560/abc832; Corrigendum: Phys. Med. Biol. 66 079501 (2021)

Sebastian Meyer, Jonathan Bortfeldt, Paulina Lämmer, Franz Englbrecht, Marco Pinto, Katrin Schnürle, Matthias Würl, Katia Parodi; Optimization and performance study of a proton CT system for pre-clinical small animal imaging; Phys. Med. Biol. 65 155008 (2020); https://epub.ub.uni-muenchen.de/72303/; https://iopscience.iop.org/article/10.1088/1361-6560/ab8afc

2019

Julie Lascaud, Ronaldo Kalunga, Sebastian Lehrack, Hans-Peter Wieser, Franz S. Englbrecht, Matthias Würl, Walter Assmann, Alessandro Stuart Savoia, Katia Parodi; Applicability of Capacitive Micromachined Ultrasonic Transducers for the detection of proton-induced thermoacoustic waves; 2019 IEEE International Ultrasonics Symposium (IUS); 143-146, 2019; https://epub.ub.uni-muenchen.de/70677/; https://doi.org/10.1109/ULTSYM.2019.8926023

Katia Parodi, Walter Assmann, Claus Belka, Jonathan Bortfeldt, Dirk-André Clevert, George Dedes, Ronaldo Kalunga, Sonja Kundel, Neeraj Kurichiyanil, Paulina Lämmer, Julie Lascaud, Kirsten Lauber, Giulio Lovatti, Sebastian Meyer, Munetaka Nitta, Marco Pinto, Mohammad J. Safari, Katrin Schnürle, Jörg Schreiber, Peter G. Thirolf, Hans-Peter Wieser, Matthias Würl; Towards a novel small animal proton irradiation platform: the SIRMIO project; Acta Oncologica; 58 10 1470-1475, 2019; https://epub.ub.uni-muenchen.de/70659/; https://doi.org/10.1080/0284186X.2019.1630752

Kurichiyanil, N, Pinto, M, Rösch, T, Kundel, S, Würl, M, Englbrecht, F, Schreiber, J, Parodi, K; Design of An Adaptable Permanent-Magnet Quadrupole Triplet for Refocusing of Energy Degraded Proton Beams for Small Animal Irradiation; Medical Physics; 46 6 E425-E425, 2019; https://epub.ub.uni-muenchen.de/70703/

Conference Contributions

2020

Julie Lascaud, Hans-Peter Wieser, Pratik Dash, Ronaldo Kalunga, Sebastian Lehrack, Walter Assmann, Katia Parodi; Investigation of the accuracy of co-registered ionoacoustic and ultrasound images in proton beams; Talk given at the IEEE NSS/MIC conference 2020; 07.11.20

Matthias Würl, Katrin Schnürle, Jonathan Bortfeldt, Cristina Oancea, Carlos Granja, Enrico Verroi, Francesco Tommasino, Katia Parodi; Development of a setup for small-animal proton imaging based on a miniaturized Timepix detector; Talk given at the 1st Workshop Trento Proton Beam Line Facility, Trento; 09.11.20; https://agenda.infn.it/event/23198/contributions/122899/contribution.pdf

Giulio Lovatti, Munetaka Nitta, Mohammad Safari, Chiara Gianoli, H.G. Kang, Andreas Zoglauer, Marco Pinto, Gerogious Dedes, Taiga Yamaya, Peter G. Thirolf, Katia Parodi; An advanced simulation and reconstruction framework for a novel in-beam PET scanner for pre-clinical proton irradiation; Poster presented at the IEEE NSS/MIC conference 2020; 05.11.20

Matthias Würl, Katrin Schnürle, Jonathan Bortfeldt, Cristina Oancea, Carlos Granja, Enrico Verroi, Francesco Tommasino, Katia Parodi; Proton Radiography for a Small-Animal Irradiation Platform based on a Miniaturized Timepix Detector; Poster presented at the IEEE NSS/MIC conference 2020; 05.11.20

Jonathan Bortfeldt, Othmar Belker, Benjamin Haubmann, Antonia Lange, David Lovric, Katrin Schnürle, Matthias Würl, Katia Parodi; Status of Gaseous Detector R&D for a Small Animal Proton Irradiation System; talk given at the RD51 Collaboration Meeting, Santiago de Compostela; 09.10.20; https://indico.cern.ch/event/889369/contributions/4042751/

Matthias Würl, Katrin Schnürle, Jonathan Bortfeldt, Katharina Niepel, Guillaume Landry, Cristina Oancea, Carlos Granja, Enrico Verroi, Francesco Tommasino, Katia Parodi; Quantitative proton radiography for a small-animal irradiation platform based on a miniaturized Timepix detector; Präsentation auf der 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik; 11.09.20; https://epub.ub.uni-muenchen.de/74258/

Pratik Dash, Julie Lascaud, Hans-Peter Wieser, Ronaldo Kalunga, Benjamin Wollant, Walter Assmann, Jonathan Bortfeldt, Marco Pinto, Neeraj Kurichiyanil, Matthias Würl, Grigory Liubchenko, Katharina Niepel, Bastian Sabel, Guillaume Landry, Kirsten Lauber, Alessandro Savoia, Katia Parodi; Investigating the co-registration of ionoacoustic and ultrasound signals along with possibilities of dose reconstruction in realistic small animal models for proton irradiation monitoring; Präsentation auf der 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik; 10.09.20; https://epub.ub.uni-muenchen.de/74259/

Larissa C. Zott, Jonathan Bortfeldt, Sonja Gerlach, Neeraj Kurichiyanil, Kirsten Lauber, Rasmus Nilsson, Matthias Würl, Erik Traneus, Marco Pinto, Katia Parodi; A Computational Framework to Validate a Prototype Planning System for a Small Animal Proton Irradiator; Präsentation auf der 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik; 09.09.20; https://epub.ub.uni-muenchen.de/75257/

Grigory Liubchenko, Matthias Würl, Katrin Schnürle, Sebastian Meyer, Jonathan Bortfeldt, Carlos Granja, Christina Oancea, Enrico Verroi, Francesco Tommasino, Katherine Vallis, Katia Parodi; Assessing the feasibility of high-Z metal (oxide) nanoparticles as contrast enhancement agents in proton imaging for a small animal irradiation platform (SIRMIO); Präsentation auf der 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik; 10.09.20;https://epub.ub.uni-muenchen.de/75196/

Munetaka Nitta, Giulio Lovatti, Mohammad Safari, Tim Binder, Han Gyu Kang, Sodai Takyu, Gerogious Dedes, Taiga Yamaya, Peter G. Thirolf, Katia Parodi; Design and detector development for an in-beam small animal PET scanner; Präsentation auf der 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik; 10.09.20; https://epub.ub.uni-muenchen.de/75193/

Katrin Schnürle, Jonathan Bortfeldt, Franz Siegfried Englbrecht, Chiara Gianoli, Jens Hartmann, Sebastian Meyer, Katharina Niepel, Guilaume Landry, Indra Yohannes, Jörg Schreiber, Katia Parodi, Matthias Würl; Entwicklung von Protonenbildgebung mit einem einzelnen integrierenden CMOS-Detektor für eine Kleintierbestrahlungsanlage; Präsentation auf der 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik; 10.09.20; https://epub.ub.uni-muenchen.de/74260/

Hans-Peter Wieser, Pratik Dash, Matthias Würl, Alessandro Stuart Savoia, Walter Assmann, Katia Parodi, Julie Lascaud; Simulation und Validierung der Detektorantwort für eine verbesserte Ionoakustik-basierte Bragg Peak Lokalisation; Präsentation auf der 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik; 10.09.20; https://epub.ub.uni-muenchen.de/74201/

Katia Parodi; Ionoacoustics for pre-clinical and clinical research in proton therapy: opportunities and challenges; Talk given at the IEEE International Ultrasonics Symposium (IUS) 2020; 06-11.09.20; https://2020.ieee-ius.org/presentation/invited-speaker/ionoacoustics-pre-clinical-and-clinical-research-proton-therapy

Katia Parodi; Towards a novel small animal proton irradiation platform for precision image-guided preclinical research; Talk given at the 62nd annual AAPM conference 2020; 14.07.20

Hans-Peter Wieser and Pratik Dash and Alessandro Stuart Savoia and Walter Assmann and Katia Parodi and Julie Lascaud; Accurate Simulation and Validation of the Detector Response for improved Bragg Peak Localization via Ionoacoustics; Poster presented at the 62nd annual AAPM conference 2020; 12.-16.07.20; https://epub.ub.uni-muenchen.de/74200/

Hans-Peter Wieser, Yuanhui Huang, Jannis Schauer, Julie Lascaud, Andriy Chmyrov, Vasilis Ntziachristos, Günther Dollinger, Walter Assmann, Katia Parodi; First Experimental Demonstration of accurate Bragg Peak Localization with ionoacoustic Tandem Phase Detection (iTPD); Poster presented at the 62nd annual AAPM conference 2020; 12.-16.07.20; https://epub.ub.uni-muenchen.de/74199/

Katia Parodi; SIRMIO: A novel platform for precision image-guided small animal proton irradiation; Talk given at the MMND (Mini‐Micro‐Nano Dosimetry) Conference, Wollongong, Australia; 12.02.20

Jona Bortfeldt, Sebastian Schinzel, Sebastian Meyer, Othmar Belker, Franz Englbrecht, Katrin Schnürle, Matthias Würl, Katia Parodi; Production and Test of an Aluminum Floating Strip Micromegas for Small Animal Proton Imaging; Talk given at the RD51 Mini-Week February 10 - 13 2020, CERN; 11.02.20

2019

Jonathan Bortfeldt, Paulina Lämmer, Sebastian Meyer, Franz Englbrecht, John Gordon, Katrin Schnürle, Matthias Würl, Katia Parodi; Novel Micropattern Gaseous Detectors for a Small Animal Proton Irradiation Platform; Poster presented at the IEEE NSS/MIC conference 2019; 30.10.19

Munetaka Nitta, Giulio Lovatti, Mohammad Safari, Gerogious Dedes, Taiga Yamaya, Peter G. Thirolf, Katia Parodi; Sensitivity comparison of LYSO and GAGG scintillators for In-beam PET Measurements; Poster presented at the IEEE NSS/MIC conference 2019; 30.10.19

Giulio Lovatti, Munetaka Nitta, Mohammad Safari, H.G. Kang, Andreas Zoglauer, Gerogious Dedes, Taiga Yamaya, Peter G. Thirolf, Katia Parodi; Design study of a novel geometrical arrangement for an in-beam small animal PET scanner; Poster presented at the IEEE NSS/MIC conference 2019; 30.10.19

Julie Lascaud, Ronaldo Kalunga, Sebastian Lehrack, Hans-Peter Wieser, Franz Siegfried Englbrecht, Matthias Würl, Walter Assmannr, Alessandro Stuart Savoia, Katia Parodi; Applicability of Capacitive Micromachined Ultrasonic Transducers for the detection of proton-induced thermoacoustic waves; Talk given at the IEEE International Ultrasonics Symposium (IUS) 2019; 07.10.19; https://epub.ub.uni-muenchen.de/70677/

Sebastian Meyer, Jonathan Bortfeldt, Paulina Lämmer, Franz Englbrecht, Katrin Schnürle, Matthias Würl, Katia Parodi; Optimierung und Performance Evaluierung eines Protonen Computertomographie Systems für präklinische Bildgebung; Talk given at the 50th Annual Meeting of the Deutsche Gesellschaft für Medizinische Physik; 20.10.19; https://epub.ub.uni-muenchen.de/75413/

Sonja Kundel, Marco Pinto, Neeraj Kurichiyanil, Matthias Würl, Franz Englbrecht, Martin Hillbrand, Daniel Köpl, Indra Yohannes, Jacobus Maarten Schippers, Jörg Schreiber, Katia Parod; Optimierung einer neuartigen Strahlführung für Kleintierbestrahlungen an einem klinischen Protonen-Therapiezentrum; Poster presented at the 50th Annual Meeting of the Deutsche Gesellschaft für Medizinische Physik; 19.09.19; https://epub.ub.uni-muenchen.de/75412/

Hans-Peter Wieser, Julie Lascaud, Sebastian Lehrack, Ronaldo Kalunga, Matthias Würl, Walter Assmann, Katia Parodi; Untersuchung des ionoakustischen effektes in heterogenen Medien zur Minimierung der reichweitenunsicherheit in der Partikeltherapie; Talk given at the 50th Annual Meeting of the Deutsche Gesellschaft für Medizinische Physik; 18.10.19; https://epub.ub.uni-muenchen.de/70701/

Jona Bortfeldt, Paulina Lämmer, Sebastian Meyer, Matthias Würl, Martin Hillbrand, Ralf Hertenberger, John Gordon, Katia Parodi; Entwicklung mikrostrukturierter Gasdetektoren für ein präklinisches Protonenbestrahlungssystem; Talk given at the 50th Annual Meeting of the Deutsche Gesellschaft für Medizinische Physik; 18.09.19; https://epub.ub.uni-muenchen.de/70699/

Katrin Schnürle, Matthias Würl, Jannik Esslinger, Sebastian Meyer, Jonathan Bortfeldt, Franz Siegfried Englbrecht, Katia Parodi; Monte-Carlo-Studie zur Protonenradiographie für die Positionsverifikation für Kleintierbestrahlungen an einem klinischen Protonen-Therapiezentrum; Talk given at the 50th Annual Meeting of the Deutsche Gesellschaft für Medizinische Physik; 18.09.19; https://epub.ub.uni-muenchen.de/70700/

Jona Bortfeldt, Paulina Lämmer, Sebastian Meyer, Franz Englbrecht, Katrin Schnürle, Matthias Würl, Katia Parodi; Ultra-Thin Gaseous Detectors for for Small Animal Proton Transmission Imaging; Talk given at the International Workshop on Detection Systems and Techniques in Nuclear and Particle Physics, Messina, Italy; 12.09.19

Neeraj Kurichiyanil, Marco Pinto, T. Rösch, Sonja Kundel, Matthias Würl, Franz Englbrecht, Jörg Schreiber, Katia Parodi; Design of An Adaptable Permanent-Magnet Quadrupole Triplet for Refocusing of Energy Degraded Proton Beams for Small Animal Irradiation; Poster presented at the 2019 AAPM Annual Meeting, San Antonio TX, USA, 14.-18.07.19; https://epub.ub.uni-muenchen.de/70703/

Sonja Kundel, Marco Pinto, Neeraj Kurichiyanil, Matthias Würl, Franz Englbrecht, Martin Hillbrand, Jörg Schreiber, Katia Parodi; Beamline optimization studies for small animal irradiation at clinical proton therapy facilities; Poster presented at the 58th Annual Conference of the Particle Therapy Co-Operative Group; 10.06.19

Katia Parodi; Towards a novel small animal proton irradiation platform: the SIRMIO project; Talk given at the Biology-Guided Adaptive Radiotherapy meeting in Aarhus (DK); 24.05.19

Jona Bortfeldt, Paulina Lämmer, Sebastian Meyer, Franz Englbrecht, Katrin Schnürle, Matthias Würl, Katia Parodi; Development of Novel Ultra-Thin Micromegas and a Time Projection Chamber for Animal Ion Transmission Tomography; talk given at the 6th International Conference on Micro Pattern Gaseous Detectors; 08.05.19; https://indico.cern.ch/event/757322/contributions/3402727/

Jona Bortfeldt, Paulina Lämmer, Sebastian Meyer, Franz Englbrecht, Katia Parodi; Development of a Time Projection Chamber for Ion Transmission Imaging; Poster presented at the Vienna Conference on Instrumentation; 20.02.19

2018

Katia Parodi; Toward precision small animal image-guided proton irradiation: the SIRMIO project; Talk given at the Annual Meeting of the Radiation Research Society in Chicago; 27.09.18

Matthias Würl, Ines Moskal, Maria Carriço, Sebastian Meyer, Franz Englbrecht, Marco Pinto, Jörg Schreiber, Katia Parodi; Feasibility study for small-animal proton radiography using passive energy variation and a single planar detector; Talk given at the 49th Annual Meeting of the Deutsche Gesellschaft für Medizinische Physik; 22.09.18; https://epub.ub.uni-muenchen.de/70698/

Theses

PhD Theses

Sebastian Meyer; On the Clinical Potential of Ion Computed Tomography with Different Detector Systems and Ion Species; PhD Thesis; Ludwig-Maximilians-Universität München; 2019; https://edoc.ub.uni-muenchen.de/24763/

Master Theses

Grigory Liubchenko; A Feasibility Study of High-Z Metal (Oxide) Nanoparticles as Contrast Agents for Proton Imaging at a Small Animal Irradiation Platform; Master's Thesis; Ludwig-Maximilians-Universität München; 2020

Pratik Dash; Feasibility Study of Ionoacoustics-based Dose Reconstruction for Small Animal Proton Irradiation Monitoring; Master's Thesis; Ludwig-Maximilians-Universität München; 2020

Sonja Kundel; Towards a Beamline for Small Animal Irradiation at Clinical Proton Therapy Facilities; Master's Thesis; Ludwig-Maximilians-Universität München; 2019

Paulina Lämmer; Studies on a Time Projection Chamber and an Ionization Chamber for Ion Transmission Imaging and Beam Monitoring; Master's Thesis; Ludwig-Maximilians-Universität München; 2019

Maximilian Grösch; Monte Carlo simulations for geometrical optimization of a novel in-beam PET scanner for a small animal proton irradiator; Master's Thesis; Ludwig-Maximilians-Universität München; 2018

Maria Cariço; Monte Carlo Investigations for a Novel Small-Animal Proton Radiographic Setup
based on a Pixelated Silicon Detector and Energy Stacking; Master's Thesis; Ludwig-Maximilians-Universität München; 2018

Bachelor Theses

Oliver Schackmann; Development of a Time Projection Chamber and its Micromegas Readout Structure for the SIRMIO Project; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2021

Antonia Lange; Characterisation of an Aluminium Floating Strip Micromegas Detector; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2021

David Lovric; Optimisation of Construction Processes for Large, Ultra Thin Micromegas Detectors; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2021

Benjamin Haubmann; Development and Characterization of 3D-Printed Ionization Chambers for Dosimetry of the SIRMIO-Platform; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2020

Georg Holthoff; Development of a Scintillation Detector for Proton Computed Tomography; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2020

Othmar Belker; Constructing and Characterizing a Micromegas with Optical Readout; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2020

Sebastian Schinzel; Development of Two-Dimensional Aluminium Readout Structures for Floating Strip Micromegas  Detectors; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2020

Jannik Esslinger; Monte Carlo Impementation of a Realistic Beam Model for a Small Animal Proton Radiography Setup; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2019

Julia Müllner; Development of an experimental bench to characterize the sensitivity of ionoacoustic sensor technologies; Bachelor's Thesis; Ludwig-Maximilians-Universität München; 2019