Experimental Medical Physics

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  • Electronic Portal Imaging Device


    State-of-the art techniques in photon radiation therapy, such as intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT), are rapidly increasing in clinical routine. These advanced technologies can provide considerably improved dose conformity to the tumor and better sparing of organs at risk. However, the complexity of these techniques adds more dosimetric uncertainties in treatment delivery. Hence, more robust Quality Assurance (QA) tests are advisable to ensure that the dose is correctly delivered as planned. To this end, an Electronic Portal Imaging Device (EPID) rigidly attached to the linear accelerator is an attractive tool showing interesting dosimetric characteristics. more

  • Advanced Treatment Planning


    Non-negligible uncertainties of the calculated proton range due to e.g. conversion of computed tomography data into stopping power ratio, patient positioning, and anatomical changes, limit the considerable advantages of proton beams in radiation therapy. Prompt gamma imaging (PG) can enable in-vivo monitoring of the proton range, but its accuracy and precision are affected by both tissue heterogeneities and counting statistics. These effects are not considered in current treatment planning systems (TPS) and intensities of most pencil beams are not optimized with respect to the precision of PG range monitoring. In our research, we investigate the possibility of re-optimizing TPS accounting for in-vivo proton range monitoring. more