Experimental Medical Physics

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Medical Physics

Peer-reviewed journals:

  1. Chan, Y., Li, M., Parodi, K., Belka, C., Landry, G. and Kurz, C. (2023). Feasibility of CycleGAN enhanced low dose CBCT imaging for prostate radiotherapy dose calculation. Physics in Medicine & Biology, 68(10), 105014. https//doi.org/10.1088/1361-6560/acccce
  2. El Naqa, I., Karolak, A., Luo, Y., Folio, L., Tarhini, A.A., Rollison, D. and Parodi, K. (2023). Translation of AI into oncology clinical practice. Oncogene, 42(42), 3089-3097. https//doi.org/10.1038/s41388-023-02826-z
  3. Huang, L., Kurz, C., Freislederer, P., Manapov, F., Corradini, S., Niyazi, M., Belka, C., Landry, G. and Riboldi, M. (2023). Simultaneous object detection and segmentation for patient-specific markerless lung tumor tracking in simulated radiographs with deep learning. Medical Physics, , mp.16705. https//doi.org/10.1002/mp.16705
  4. Kalunga, R., Wieser, H.-P., Dash, P., Würl, M., Riboldi, M., Schreiber, J., Assmann, W., Parodi, K. and Lascaud, J. (2023). On the robustness of multilateration of ionoacoustic signals for localization of the Bragg peak at pre-clinical proton beam energies in water. Physics in Medicine & Biology, 68(10), 105010. https//doi.org/10.1088/1361-6560/acc9f7
  5. Lascaud, J. and Parodi, K. (2023). On the potential biological impact of radiation-induced acoustic emissions during ultra-high dose rate electron radiotherapy: a preliminary study. Physics in Medicine & Biology, 68(5), 05LT01. https//doi.org/10.1088/1361-6560/acb9ce
  6. Liprandi, S., Takyu, S., Safari, M., Binder, T., Dedes, G., Kamada, K., Kawula, M., Mohammadi, A., Nishikido, F., Valencia-Lozano, I.I., Viegas, R., Yamaya, T., Parodi, K. and Thirolf, P.G. (2023). Compton Camera Arrangement With a Monolithic LaBr _3 (Ce) Scintillator and Pixelated GAGG Detector for Medical Imaging. IEEE Transactions on Radiation and Plasma Medical Sciences, 7(7), 764-774. https//doi.org/10.1109/TRPMS.2023.3282838
  7. Lombardo, E., Dhont, J., Page, D., Garibaldi, C., Künzel, L.A., Hurkmans, C., Tijssen, R.H., Paganelli, C., Liu, P.Z., Keall, P.J., Riboldi, M., Kurz, C., Landry, G., Cusumano, D., Fusella, M. and Placidi, L. (2023). Real-time motion management in MRI-guided radiotherapy: Current status and AI-enabled prospects. Radiotherapy and Oncology, , 109970. https//doi.org/10.1016/j.radonc.2023.109970
  8. Lombardo, E., Liu, P.Z.Y., Waddington, D.E.J., Grover, J., Whelan, B., Wong, E., Reiner, M., Corradini, S., Belka, C., Riboldi, M., Kurz, C., Landry, G. and Keall, P.J. (2023). Experimental comparison of linear regression and LSTM motion prediction models for MLC-tracking on an MRI-linac. Medical Physics, , mp.16770. https//doi.org/10.1002/mp.16770
  9. Lombardo, E., Rabe, M., Xiong, Y., Nierer, L., Cusumano, D., Placidi, L., Boldrini, L., Corradini, S., Niyazi, M., Reiner, M., Belka, C., Kurz, C., Riboldi, M. and Landry, G. (2023). Evaluation of real-time tumor contour prediction using LSTM networks for MR-guided radiotherapy. Radiotherapy and Oncology, 182, 109555. https//doi.org/10.1016/j.radonc.2023.109555
  10. Lovatti, G., Nitta, M., Javad Safari, M., Gianoli, C., Pinto, M., Dedes, G., Zoglauer, A., Thirolf, P.G. and Parodi, K. (2023). Design study of a novel geometrical arrangement for an in-beam small animal positron emission tomography scanner. Physics in Medicine & Biology, 68(23), 235005. https//doi.org/10.1088/1361-6560/ad0879
  11. Marants, R., Tattenberg, S., Scholey, J., Kaza, E., Miao, X., Benkert, T., Magneson, O., Fischer, J., Vinas, L., Niepel, K., Bortfeld, T., Landry, G., Parodi, K., Verburg, J. and Sudhyadhom, A. (2023). Validation of an MR-based multimodal method for molecular composition and proton stopping power ratio determination using ex vivo animal tissues and tissue-mimicking phantoms. Physics in Medicine & Biology, 68(17), 175033. https//doi.org/10.1088/1361-6560/ace876
  12. Martins, J.C., Maier, J., Gianoli, C., Neppl, S., Dedes, G., Alhazmi, A., Veloza, S., Reiner, M., Belka, C., Kachelrieß, M. and Parodi, K. (2023). Towards real-time EPID-based 3D in vivo dosimetry for IMRT with Deep Neural Networks: A feasibility study. Physica Medica, 114, 103148. https//doi.org/10.1016/j.ejmp.2023.103148
  13. Palaniappan, P., Knudsen, Y., Meyer, S., Gianoli, C., Schnürle, K., Würl, M., Bortfeldt, J., Parodi, K. and Riboldi, M. (2023). Multi-stage image registration based on list-mode proton radiographies for small animal proton irradiation: A simulation study. Zeitschrift für Medizinische Physik, , S0939388923000454. https//doi.org/10.1016/j.zemedi.2023.04.003
  14. Parodi, K., Yamaya, T. and Moskal, P. (2023). Experience and new prospects of PET imaging for ion beam therapy monitoring. Zeitschrift für Medizinische Physik, 33(1), 22-34. https//doi.org/10.1016/j.zemedi.2022.11.001
  15. Rabe, M., Paganelli, C., Schmitz, H.P., Meschini, G., Riboldi, M., Hofmaier, J., Nierer-Kohlhase, L., Dinkel, J., Reiner, M., Parodi, K., Belka, C., Landry, G., Kurz, C. and Kamp, F. (2023). Continuous time-resolved estimated synthetic 4D-CTs for dose reconstruction of lung tumor treatments at a 0.35 T MR-linac. Physics in Medicine & Biology, https//doi.org/10.1088/1361-6560/acf6f0
  16. Rädler, M., Buizza, G., Kawula, M., Palaniappan, P., Gianoli, C., Baroni, G., Paganelli, C., Parodi, K. and Riboldi, M. (2023). Impact of secondary particles on the magnetic field generated by a proton pencil beam: a finite-element analysis based on Geant4-DNA simulations. Medical Physics, 50(2), 1000-1018. https//doi.org/10.1002/mp.16062
  17. Ribeiro, M.F., Marschner, S., Kawula, M., Rabe, M., Corradini, S., Belka, C., Riboldi, M., Landry, G. and Kurz, C. (2023). Deep learning based automatic segmentation of organs-at-risk for 0.35 T MRgRT of lung tumors. Radiation Oncology, 18(1), 135. https//doi.org/10.1186/s13014-023-02330-4
  18. Schauer, J., Wieser, H.-P., Lascaud, J., Huang, Y., Vidal, M., Herault, J., Ntziachristos, V., Dollinger, G. and Parodi, K. (2023). Range verification of a clinical proton beam in an abdominal phantom by co-registration of ionoacoustics and ultrasound. Physics in Medicine & Biology, 68(12), 125009. https//doi.org/10.1088/1361-6560/acd834
  19. Schmitz, H., Rabe, M., Janssens, G., Rit, S., Parodi, K., Belka, C., Kamp, F., Landry, G. and Kurz, C. (2023). Scatter correction of 4D cone beam computed tomography to detect dosimetric effects due to anatomical changes in proton therapy for lung cancer. Medical Physics, , mp.16335. https//doi.org/10.1002/mp.16335
  20. Schmitz, H., Thummerer, A., Kawula, M., Lombardo, E., Parodi, K., Belka, C., Kamp, F., Kurz, C. and Landry, G. (2023). ScatterNet for projection-based 4D cone-beam computed tomography intensity correction of lung cancer patients. Physics and Imaging in Radiation Oncology, 27, 100482. https//doi.org/10.1016/j.phro.2023.100482
  21. Sui, Z., Palaniappan, P., Brenner, J., Paganelli, C., Kurz, C., Landry, G. and Riboldi, M. (2023). Intra-frame motion deterioration effects and deep-learning-based compensation in MR-guided radiotherapy. Medical Physics, , mp.16702. https//doi.org/10.1002/mp.16702
  22. Valencia Lozano, I., Dedes, G., Peterson, S., Mackin, D., Zoglauer, A., Beddar, S., Avery, S., Polf, J. and Parodi, K. (2023). Comparison of reconstructed prompt gamma emissions using maximum likelihood estimation and origin ensemble algorithms for a Compton camera system tailored to proton range monitoring. Zeitschrift für Medizinische Physik, 33(2), 124-134. https//doi.org/10.1016/j.zemedi.2022.04.005
  23. Verhaegen, F., Butterworth, K.T., Chalmers, A.J., Coppes, R.P., De Ruysscher, D., Dobiasch, S., Fenwick, J.D., Granton, P.V., Heijmans, S.H.J., Hill, M.A., Koumenis, C., Lauber, K., Marples, B., Parodi, K., Persoon, L.C.G.G., Staut, N., Subiel, A., Vaes, R.D.W., Van Hoof, S., Verginadis, I.L., Wilkens, J.J., Williams, K.J., Wilson, G.D. and Dubois, L.J. (2023). Roadmap for precision preclinical x-ray radiation studies. Physics in Medicine & Biology, 68(6), 06RM01. https//doi.org/10.1088/1361-6560/acaf45
  24. Xiong, Y., Rabe, M., Nierer, L., Kawula, M., Corradini, S., Belka, C., Riboldi, M., Landry, G. and Kurz, C. (2023). Assessment of intrafractional prostate motion and its dosimetric impact in MRI-guided online adaptive radiotherapy with gating. Strahlentherapie und Onkologie, 199(6), 544-553. https//doi.org/10.1007/s00066-022-02005-1


Peer-reviewed journals:

  1. N. Weiße, F. Balling, A. Döpp, L. Doyle, J. Esslinger, J. Gebhard, L.D. Geulig, S. Gerlach, M. Gilljohann, F. Haberstroh, F. Irshad, S. Karsch, J. Lin, A. Münzer, Jörg Schreiber, F. Schweiger, D. Siebert, and P.G. Thirolf, Tango Controls and data pipeline for petawatt laser experiments, High Power Laser Science and Engineering 1-8 (2023), doi:10.1017/hpl.2023.17

Abstracts and conference proceedings:

  1. Laura Desiree Geulig, Erin Grace Fitzpatrick, Maximilian Weiser, Veronika Kratzer, Vitus Magin, Masoud Afshari, Jörg Schreiber, and Peter G. Thirolf, Laser-Driven Acceleration of Gold Ions, Verhandl. DPG (VI), 58, A 3.2 (2023)
  2. Erin G. Fitzpatrick, Laura D. Geulig, Maximilian J. Weiser, Veronika Kratzer, Vitus Magin, Florian H. Lindner, and Peter G. Thirolf, Towards studying the collective effects in laser-driven heavy ion acceleration, Verhandl. DPG (VI), 58, A 20.4 (2023)
  3. Vitus Magin, Laura D. Geulig, Erin G. Fitzpatrick, Maximilian J. Weiser, Veronika Kratzer, and Peter G. Thirolf, Integration of a nano-Foil Target Positioning System for High-Power Laser Ion Acceleration, Verhandl. DPG (VI), 58, A 20.19 (2023)
  4. Veronika Kratzer, Laura D. Geulig, Erin G. Fitzpatrick, Florian H. Lindner, Vitus Magin, Maximilian J. Weiser, and Peter G. Thirolf, Spectroscopic Real-Time Temperature Diagnostic for Laser Heated Thin Gold Foils, Verhandl. DPG (VI), 58, A 20.22 (2023)
  5. V. Kratzer, L.D. Geulig, E.G. Fitzpatrick, F.H. Lindner, V. Magin, M.J. Weiser, and P.G. Thirolf, Spectroscopic Real-Time Temperature Diagnostic for Laser Heated Thin Gold Foils, SPIE Optics and Optoelectronics, Proceedings Vol. 12583, 1258307 (2023), https://doi.org/10.1117/12.2665472

Nuclear Physics

Peer-reviewed journals:

  1. Deary, J., Scheck, M., Schwengner, R., O’Donnell, D., Bemmerer, D., Beyer, R., Hensel, T., Junghans, A.R., Kögler, T., Müller, S.E., Römer, K., Schmidt, K., Turkat, S., Urlaß, S., Wagner, A., Bowry, M., Adsley, P., Agar, O., Chapman, R., Crespi, F.C.L., Doherty, D.T., Gayer, U.F., Herzberg, R.-D., Isaak, J., Janssens, R.V.F., Kröll, T., Löher, B., Nara Singh, B.S., Von Neumann-Cosel, P., Pellegri, L., Peters, E.E., Rainovski, G., Savran, D., Smith, J.F., Spieker, M., Thirolf, P.G., Triambak, S., Tornow, W., Venhart, M., Wiedeking, M., Wieland, O., Yates, S.W. and Zilges, A. (2023). Photo-response of the $$N=Z$$ nucleus $$textasciicircum24\$$Mg. The European Physical Journal A, 59(9), 198. https//doi.org/10.1140/epja/s10050-023-01111-7
  2. Jin, J., Bekker, H., Kirschbaum, T., Litvinov, Y.A., Pálffy, A., Sommerfeldt, J., Surzhykov, A., Thirolf, P.G. and Budker, D. (2023). Excitation and probing of low-energy nuclear states at high-energy storage rings. Physical Review Research, 5(2), 023134. https//doi.org/10.1103/PhysRevResearch.5.023134
  3. Kraemer, S., Moens, J., Athanasakis-Kaklamanakis, M., Bara, S., Beeks, K., Chhetri, P., Chrysalidis, K., Claessens, A., Cocolios, T.E., Correia, J.G.M., Witte, H.D., Ferrer, R., Geldhof, S., Heinke, R., Hosseini, N., Huyse, M., Köster, U., Kudryavtsev, Y., Laatiaoui, M., Lica, R., Magchiels, G., Manea, V., Merckling, C., Pereira, L.M.C., Raeder, S., Schumm, T., Sels, S., Thirolf, P.G., Tunhuma, S.M., Van Den Bergh, P., Van Duppen, P., Vantomme, A., Verlinde, M., Villarreal, R. and Wahl, U. (2023). Observation of the radiative decay of the 229Th nuclear clock isomer. Nature, 617(7962), 706-710. https//doi.org/10.1038/s41586-023-05894-z
  4. Scharl, K., Ding, S., Holthoff, G., Hussain, M.I., Kraemer, S., Löbell, L., Moritz, D., Rozibakieva, T., Seiferle, B., Zacherl, F. and Thirolf, P.G. (2023). Setup for the Ionic Lifetime Measurement of the 229mTh3+ Nuclear Clock Isomer. Atoms, 11(7), 108. https//doi.org/10.3390/atoms11070108
  5. Zhao, J., Amanbayev, D., Dickel, T., Miskun, I., Plaß, W., Tortorelli, N., San Andrés, S.A., Beck, S., Bergmann, J., Brencic, Z., Constantin, P., Geissel, H., Greiner, F., Gröf, L., Hornung, C., Kuzminchuk, N., Kripkó-Koncz, G., Mardor, I., Pohjalainen, I., Scheidenberger, C., Thirolf, P., Bagchi, S., Haettner, E., Kazantseva, E., Kostyleva, D., Oberstedt, A., Pietri, S., Reiter, M., Tanaka, Y., Wada, M., Balabanski, D., Benyamin, D., Harakeh, M., Hubbard, N., Kalantar-Nayestanaki, N., Mollaebrahimi, A., Mukha, I., Narang, M., Niwase, T., Patyk, Z., Purushothaman, S., Rotaru, A., Spv ataru, A., Stanic, G., Vencelj, M., Weick, H. and Yu, J. (2024). Increasing the rate capability for the cryogenic stopping cell of the FRS Ion Catcher. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 547, 165175. https//doi.org/10.1016/j.nimb.2023.165175

Abstracts and conference proceedings:

  1. Kevin Scharl, Daniel Moritz, Mahmood Hussain, Sandro Kraemer, Lilli Löbell, Florian Zacherl, Shiqian Ding, Benedict Seiferle, and Peter G. Thirolf, Recent Developments towards the Lifetime Measurement of the 229mTh Nuclear Clock Isomer,  Verhandl. DPG (VI), 58, Q 51.6 (2023)
  2. Mahmood Hussain, Johannes Weitenberg, Stephan H. Wissenberg, Tamila Rozibakieva, Hans-Dieter Hoffmann, Constantin L. Häfner, and Peter G. Thirolf, Towards VUV laser spectroscopy of the nuclear clock isomer 229mTh, Verhandl. DPG (VI), 58, Q 51.7 (2023)
  3. Tamila Rozibakieva, Stephan H. Wissenberg, Hans-Dieter Hoffmann, Constantin L. Häfner, Peter G. Thirolf, and Johannes Weitenberg, Tailored transverse field distributions in an enhancement resonator for high harmonic generation, Verhandl. DPG (VI), 58, Q 10.3 (2023)
  4. Lilli Löbell, Sandro Kraemer, Daniel Moritz, Kevin Scharl, Benedict Seiferle, Lars von der Wense, Florian Zacherl, and Peter Thirolf, Investigation of the internal conversion lifetime of 229mTh in a solid, Verhandl. DPG (VI), 58, HK 61.3 (2023)
  5. Daniel Moritz, Sandro Kraemer, Lilli Löbell, Kevin Scharl, Benedict Seiferle, Lars von der Wense, Florian Zacherl, and Peter G. Thirolf, Investigations of the internal conversion lifetime of 229mTh on various metal surfaces, Verhandl. DPG (VI), 58, HK 61.4 (2023)
  6. Laura Desiree Geulig, Erin Grace Fitzpatrick, Maximilian J. Weiser, Veronika Kratzer, Vitus Magin, Masoud Afshari, Jörg Schreiber, and Peter G. Thirolf, Laser-Driven Acceleration of Gold Ions, Verhandl. DPG (VI), 58, AKBP 6.2 (2023)

Outreach article:

  1. Peter G. Thirolf, Sandro Kraemer, Johannes Weitenberg, Mehr als ein hochgenauer Zeitmesser, Physik in unserer Zeit (2023), https://doi.org/10.1002/piuz.202301696

Detector Development and High Energy Physics

Books and Book Chapters



Thesis Works



Master Thesis (internal):

H. Geesmann: Commissioning and Characterization of different scintillator-based prototype Compton Camera setups with segmented SiPM readout

C. Steinbrecht: Development of FPGA-based Beam Monitoring and Control System for SIRMIO

G. Holthoff: Commissioning of the SIRMIO Tracking pCT System 

M. Gerlei: Feasibility of Contrast Agent Enhanced Ionoacoustics in Preclinical and Clinical Proton Therapy

H. Geesmann: Commissioning and Characterization of different scintillator-based prototype Compton Camera setups with          segmented SiPM readout

Bachelor Thesis (internal):

M. Gloeckner: Charakterisierung der Micromegas Spurdetektoren für das SIRMIO Projekt

H. Forsthuber: Studien zur Kühlung von Micromegas Detektoren 

P. Schintzel: Verbesserung der Zeitprojektionskammer des SIRMIO Proton-CT Systems

F. Mislik: Investigating Out-of-Field Dose Contributions in a Patient-Sized Phantom

J. Altmann: Entwicklung eines portablen rezirkulierenden Gassystems für Micromegas

V. Magin: Commissioning of the nano-Foil Target Positioning System

F. Zacherl: Setup of a Fabry-Perot Cavity to Characterize the Lasers for Hyperfine Structure Spectroscopy of 229mTh3+

Master Thesis (external):


Bachelor Thesis (external):

Zulassungsarbeit (State exam thesis):