Experimental Medical Physics

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Peer-reviewed journals

Medical Physics

  1. Landry G, Dedes G, Zöllner C, Handrack J, Janssens G, Orban de Xivry J, Reiner M, Paganelli C, Riboldi M, Kamp F, Söhn M, Wilkens JJ, Baroni G, Belka C, Parodi K. Phantom based evaluation of CT to CBCT image registration for proton therapy dose recalculation. Phys Med Biol. 2015 Jan 21;60(2):595-613
  2. W. Assmann, S. Kellnberger, S. Reinhardt, S. Lehrack, A. Edlich, P. G. Thirolf, M. Moser, G. Dollinger, M. Omar, V. Ntziachristos and K. Parodi, Ionoacoustic characterization of the proton Bragg peak with submillimeter accuracy, Med. Phys. 42, 567 (2015).
  3. S. Reinhardt, M. Würl, C. Greubel, N. Humble, J. J. Wilkens, M. Hillbrand, A. Mairani, W. Assmann, K. Parodi, Investigation of EBT2 and EBT3 films for proton dosimetry in the 4–20 MeV energy range
    Radiation and Environmental Biophysics (January 2015).
  4. M. Pinto, M. Bajard, S. Brons, M. Chevallier, D. Dauvergne, G. Dedes, M. De Rydt, N. Freud, J. Krimmer, C. La Tessa, JM Létang, K. Parodi, R. Pleskač, D. Prieels, C. Ray, I. Rinaldi, F. Roellinghoff, D. Schardt, E. Testa, M. Testa, Absolute prompt-gamma yield measurements for ion beam therapy monitoring, Phys Med Biol. 2015 Jan 21;60(2):565-94. doi: 10.1088/0031-9155/60/2/565. Epub 2014 Dec 30.
  5. SP Nischwitz, J. Bauer, T. Welzel, H.  Rief, O. Jäkel, T. Haberer, K. Frey, J. Debus, K. Parodi, SE Combs, S. Rieken. Clinical implementation and range evaluation of in vivo PET dosimetry for particle irradiation in patients with primary glioma. Radiother Oncol. 2015, S0167-8140(15)00161-9
  6. G. Landry, R. Nijhuis, G. Dedes, J. Handrack, C. Thieke, G. Janssens, J. Orban de Xivry, M.  Reiner, F.  Kamp, JJ Wilkens, C. Paganelli, M. Riboldi, G. Baroni, U. Ganswindt, C. Belka, K. Parodi. Investigating CT to CBCT image registration for head and neck proton therapy as a tool for daily dose recalculation. Med Phys. 2015 42(3):1354-66
  7. A. Troeller, D. Yan, O. Marina, D. Schulze, M. Alber, K. Parodi, C. Belka, M. Söhn. Comparison and limitations of DVH-based NTCP models derived from 3D-CRT and IMRT data for prediction of gastrointestinal toxicities in prostate cancer patients by using propensity score matched pair analysis. Int J Radiat Oncol Biol Phys. 2015 91(2):435-43
  8. H. Ballhausen, S. Hieber, M. Li K. Parodi, C. Belka, M. Reiner. Linearity of patient positioning detection : A phantom study of skin markers, cone beam computed tomography, and 3D ultrasound. Strahlenther Onkol. 2015 Jan 30.
  9. K. Parodi and W. Assmann, Ionoacoustics: A new direct method for range verification, Mod. Phys. Lett. A 30, 1540025 (2015) [11 pages] DOI: 10.1142/S0217732315400258
  10. VE Bellinzona, M. Ciocca, A. Embriaco, A. Fontana, A. Mairani, M. Mori, K. Parodi: On the parametrization of lateral dose profiles in proton radiation therapy. Phys Med. 2015  doi: 10.1016[Epub ahead of print]
  11. H. Ballhausen, BD Ballhausen, M. Lachaine, M Li, K. Parodi, C. Belka, M. Reiner: Surface refraction of sound waves affects calibration of three-dimensional ultrasound. Radiat Oncol. 2015 10(1):119
  12. P.G. Thirolf, C. Lang and K. Parodi, Perspectives for highly-sensitive PET-based medical imaging using beta^+ - gamma coincidences, Acta Physica Polonica A 127, 1441 (2015).
  13. D. Hansen, J. Seco, T. Sangild, T.S. Sorensen, J.B.B. Petersen, J.E. Wildberger, F. Verhaegen, G. Landry, A simulation study on proton CT stopping power accuracy using dual energy CT scans as benchmark. Acta Oncologica (2015) early online.
  14. E. Adolfsson, S. White, G. Landry, E Lund, H Gustafsson, F Verhaegen, B Reniers, ÅC Tedgren, GA Carlsson, Measurement of absorbed dose to water around an electronic brachytherapy source. Comparison of two dosimetry systems: lithium formate EPR dosimeters and radiochromic EBT2 film. Physics in Medicine & Biology (2015) vol. 60 (9) pp. 3869-3882.
  15. C. Kurz, J. Bauer, D. Unholtz, D. Richter, K. Stützer, C. Bert, K. Parodi, 4D offline PET-based treatment verification in scanned ion beam therapy: a phantom study. Phys Med Biol. 2015 Aug 3;60(16):6227-6246
  16. P. Cambraia Lopes, E. Clementel, P. Crespo, S. Henrotin, J. Huizenga, G. Janssens, K. Parodi, D. Prieels, F. Roellinghoff, J. Smeets,   F. Stichelbaut, DR Schaart, Time-resolved imaging of prompt-gamma rays for proton range verification using a knife-edge slit camera based on digital photon counters. Phys Med Biol. 2015 Aug 7;60(15):6063-85.
  17. C. Kurz, G. Dedes, A. Resch, M. Reiner, U. Ganswindt, R. Nijhuis, C. Thieke, C. Belka, K. Parodi, G. Landry, Comparing cone-beam CT intensity correction methods for dose recalculation in adaptive intensity-modulated photon and proton therapy for head and neck cancer. Acta Oncol. 2015 Jul 22:1-7.
  18. C. Kurz, J. Bauer, M. Conti, L. Guérin, L. Eriksson, K. Parodi, Investigating the limits of PET/CT imaging at very low true count rates and high random fractions in ion-beam therapy monitoring.  Med Phys. 2015 Jul;42(7):3979.
  19. C. Gianoli, M. Riboldi, G. Fontana, C. Kurz, K. Parodi, G A Baroni, sinogram warping strategy for pre-reconstruction 4D PET optimization. Med Biol Eng Comput. 2015.
  20. K. Parodi, On- and off-line monitoring of ion beam treatment, Nucl. Instrum. Methods A, 2015.
  21. G. Landry, M. Gaudreault, W. van Elmpt, J. E. Wildberger, F. Verhaegen, Improved dose calculation accuracy for low energybrachytherapy by optimizing dual energy CT imaging protocolsfor noise reduction using sinogram affirmed iterative reconstruction, doi:10.1016/j.zemedi.2015.09.001, Zeitschrift für Medizinische Physik, Sept. 2015
  22. K. Roemer, G.Pausch, D. Bemmerer, M. Berthel, A,. Dreyer, C. Golnik, F. Huesco-Gonzalez, T. Kormoll, J. Petzoldt, H. Rohling, P.G. Thirolf, A. Wagner, L. Wagner, D. Weinberger, F. Fiedler, Characterization of Scintillator Crystals for Usage as Prompt Gamma Monitors in Particle Therapy, Jour. of Instrumentation 10, P10033 (2015)
  23. S. Aldawood, I. Castelhano, R. Gernhäuser, H. v.d. Kolff, C. Lang, R. Lutter, L. Maier, T. Marinsek, D.R. Schaart, K. Parodi, P.G. Thirolf, Comparative characterization study of a LaBr3(Ce) scintillation crystal in two surface wrapping scenarios: absorptive and reflective, Frontiers in Oncology 5, 270 (2015).
  24. J. Polf and K. Parodi, Imaging particle beams for cancer treatment, Physics Today 68 (10), 28 (2015).
  25. N. Arbor, D. Dauvergne, G. Dedes, JM Létang, K. Parodi, CT Quiñones, E. Testa, S. Rit,  Monte Carlo comparison of x-ray and proton CT for range calculations of proton therapy beams, Phys Med Biol. 2015 Oct 7;60(19):7585-99.
  26. F. Kamp, G. Cabal, A. Mairani, K. Parodi, JJ. Wilkens, DJ Carlson, Fast Biological Modeling for Voxel-based Heavy Ion Treatment Planning Using the Mechanistic Repair-Misrepair-Fixation Model and Nuclear Fragment Spectra, Int J Radiat Oncol Biol Phys. 2015 Nov 1;93(3):557-68.
  27. S. Schmid, G. Landry, C. Thieke, F. Verhaegen, U. Ganswindt, C. Belka, K. Parodi, G. Dedes, Monte Carlo study on the sensitivity of prompt gamma imaging to proton range variations due to interfractional changes in prostate cancer patients, Phys Med Biol. 2015 Nov 18;60(24):9329-9347.
  28. N. Krah, M. Testa, S. Brons, O. Jäkel, K. Parodi, B. Voss, I. Rinaldi,  An advanced image processing method to improve the spatial resolution of ion radiographies, Phys Med Biol. 2015 Nov 7;60(21):8525-47.
  29. K. Parodi,  Vision 20/20: Positron emission tomography in radiation therapy planning, delivery, and monitoring, Med Phys. 2015 Dec;42(12):7153.
  30. Schwaab J, Kurz C, Sarti C, Bongers A, Schoenahl F, Bert C, Debus J, Parodi K, Jenne JW, First Steps Toward Ultrasound-Based Motion Compensation for Imaging and Therapy: Calibration with an Optical System and 4D PET Imaging, Front Oncol. 5 (2015) 258


Nuclear Physics

  1. P.G. Thirolf, From Laser-Particle Acceleration to the Synthesis of Extremely Neutron Rich Isotopes via the Novel Fission-Fusion Mechanism, AIP Conf. Proc. 1645, 210 (2015).
  2. L. v.d. Wense, B. Seiferle, M. Laatiaoui, P.G. Thirolf, Determination of the extraction efficiency for 233U source
    recoil ions from the MLL buffer-gas stopping cell, Eur. Phys. Jour. A 51 (2015) 29.
  3. L. Csige, M. Csatlos, T. Faestermann, J. Gulyas, D. Habs, A. Krasznahorkay, P.G. Thirolf, T.G. Tornyi, H.-F. Wirth,
    Transmission resonance spectroscopy of the doubly odd 238Np in (d,pf) reaction, Acta Phys. Pol. B 46, 559 (2015).
  4. J. Jolie, J.-M. Regis, D. Wilmsen, S. Ahmed, M. Pfeiffer, N. Saed-Samii, N. Warr, A. Blanc, M. Jentschel, U. Köster, P. Mutti, T. Soldner, G. Simpson, G. De France, W. Urban, F. Drouet, A. Vancraeyenest, P. Baczyk, M. Czerwinski, A. Korgul, C. Mazzocchi, T. Rzaca-Urban, A. Bruce, O.J. Roberts, L.M. Fraile, V. Paziy, A. Ignatov, S. Ilieva, Th. Kröll, M. Scheck, M. Thürauf, D. Ivanova, S. Kisyov, S. Lalkovski, Z. Podolyak, P.H. Regan, W. Korten, M. Zielinska, M.D. Salsac, D. Habs, P. Thirolf, C.A. Ur1, C. Bernards, R.F. Casten, N. Cooper, V. Werner, R.B. Cakirli, S. Leoni, G. Benzoni, G. Bocchi, S. Bottoni, F.C.L. Crespi, B. Fornal, N. Cieplicka, B. Szpak, C. Petrache, R. Leguillon, R. John, C. Lorenz, R. Massarczyk, R. Schwengner, D. Curien, L. Sengele, R. Lozeva, N. Marginean, R. Lica,
    The (n,gamma) campaigns at EXILL, EPJ Web of Conferences 93, 01014 (2015).
  5. A.I. Levon, P. Alexa, G. Graw, C. Günther, R. Hertenberger, S. Pascu, P.G. Thirolf, H.-F. Wirth, Study of 232U in the (p,t) reaction: more information on 0+ excitations, Phys. Rev. C 92 (2015) 064319


Abstracts and conference proceedings

Medical Physics

  1. Yoshida E, Tashima H, Levin CS, Parodi K, Yamaya T. Simulation study of a DOI-based PET-Compton imaging system for positron emitters. In Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2015 IEEE 2015 Oct 31 (pp. 1-2). IEEE.
  2. Tashima H, Kurz C, Yoshida E, Debus J, Parodi K, Yamaya T. Patient data-based Monte Carlo simulation of in-beam single-ring OpenPET imaging. In Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2015 IEEE 2015 Oct 31 (pp. 1-3). IEEE.
  3. S. Aldawood, S. Liprandi, T. Marinsek, J. Bortfeldt, L. Maier, C. Lang, H. van der Kolff, I. Castelhano, R. Lutter, G. Dedes, R Gernhäuser, D. R. Schaart, K. Parodi, and P. G. Thirolf,  Development of a Compton Camera for online ion beam range verification via prompt γ detection, Verhandl. DPG (VI) 50, HK 12.4 (2015).
  4. S. Liprandi, S. Aldawood, T. Marinsek, J. Bortfeldt, L. Maier, C. Lang, H. van der Kolff, I. Castelhano, R. Lutter, G. Dedes, R. Gernhäuser, D. R. Schaart, K. Parodi, and P. G. Thirolf, Commissioning of the scatter component of a Compton camera consisting of a stack of Si strip detectors, Verhandl. DPG (VI) 50, HK 48.48 (2015).
  5. T. Marinsek, S. Aldawood, S. Liprandi, J. Bortfeldt, L. Maier, C. Lang, H. van der Kolff, I. Castelhano, R. Lutter, G. Dedes, R. Gernhäuser, D. R. Schaart, K. Parodi, and P. G. Thirolf, Characterization of Compton camera LaBr3 absorber detector, Verhandl. DPG (VI) 50, HK 48.50 (2015).
  6. S. Reinhardt, M. Wuerl, C. Greubel, J. Wilkens, M. Hillbrand, A. Mairani, W. Assmann, K. Parod, SU-E-T-533: LET Dependence Correction of Radiochromic Films for Application in Low Energy Proton Irradiation. Med Phys. 2015 Jun;42(6):3458
  7. N. Qin, M. Pinto, Z. Tian, G. Dedes, A. Pompos, S. Jiang, K. Parodi, X. Jia, SU-E-T-499: Initial Developments of An OpenCL-Based Cross-Platform Monte Carlo Dose Engine for Carbon Ion Therapy.  Med Phys. 2015 Jun;42(6):3449
  8. I. Rinaldi, K. Parodi, N. Krah, SU-C-204-02: Improved Patient-Specific Optimization of the Stopping Power Calibration for Proton Therapy Planning Using a Single Proton RadiographyMed Phys. 2015 Jun;42(6):3199
  9. I. Rinaldi, K. Parodi, N. Krah, WE-EF-303-04: An Advanced Image Processing Method to Improve the Spatial Resolution of Proton Radiographies. Med Phys. 2015 Jun;42(6):3678
  10. G. Dedes, Y. Asano, N. Arbor, D. Dauvergne, J. Letang, E. Testa, S. Rit, K. Parodi, SU-E-J-147: Monte Carlo Study of the Precision and Accuracy of Proton CT Reconstructed Relative Stopping Power Maps. Med Phys. 2015 Jun;42(6):3298
  11. K. Kroeniger, M. Herzog, G. Landry, E. Traneus, G. Dedes, K. Parodi,  SU-C-204-01: A Fast Analytical Approach for Prompt Gamma and PET Predictions in a TPS for Proton Range Verification. Med Phys. 2015 Jun;42(6):3199.
  12. C. Kurz, G. Dedes, A. Resch, M. Reiner, G. Janssens, J. Obarn de Xivry, F. Kamp, J.J. Wilkens, C. Thieke, R. Nijhuis, U. Ganswindt, C. Belka, K. Parodi, G. Landry, CBCT dose recalculation strategies to support adaptive IMRT and IMPT of head and neck cancer patients, DGMP Marburg 2015, Abstractband p. 115-116, ISBN: 978-3-9816508-8-4.
  13. S. Reinhardt, M. Würl, C. Greubel, J. Wilkens, M. Hillbrand, A. Mairani, W. Assmann, K. Parodi, Correction of the LET dependence of radiochromic films for application in low-energy laser-driven proton irradiation, DGMP Marburg 2015, Abstractband p. 160-161, ISBN: 978-3-9816508-8-4.
  14. F. Englbrecht, M. Würl, D. Haffa, C. Kreuzer, S. Reinhardt, J. Schreiber, K. Parodi, Monte-Carlo studies for the development of laser-driven proton radiography, DGMP Marburg 2015, Abstractband p. 192, ISBN: 978-3-9816508-8-4.
  15. S. Meyer, L. Magallanes, T. Tessonnier, G. Landry, G. Dedes, I. Rinaldi, B. Voss, O. Jäkel, C. Gianoli, K. Parodi, A systematic Monte-Carlo study of the influence of different acquisition and detector parameters on the image quality of carbon ion radiography and tomography using a range telescope, DGMP Marburg 2015, Abstractband p. 115-116, ISBN: 978-3-9816508-8-4.
  16. P. Thirolf, T. Marinsek, S. Aldawood, M. Böhmer, J. Bortfeldt, I. Castelhano, R. Gernhäuser, H. van der Kolff, C. Lang, S. Liprandi, L. Maier, D.R. Schaart, K. Parodi, Determination of the photon hit position in the monolithic absorber of a Compton camera, DGMP Marburg 2015, Abstractband p. 288-289, ISBN: 978-3-9816508-8-4.
  17. K. Kroeniger, M.L. Herzog, G. Landry, E. Traneus, G. Dedes, K. Parodi, A fast analytical approach for prompt gamma and PET predictions in a TPS for proton range verification, DGMP Marburg 2015, Abstractband p. 290-291, ISBN: 978-3-9816508-8-4.
  18. S. Lehrack, W. Assmann, A. Maaß, G. Dedes, S. Reinhardt, P. Thirolf, G. Dollinger, K. Parodi, Ionoacoustics – Optimizing data analysis and experimental setup towards application at clinical energies, DGMP Marburg 2015, Abstractband p. 292, ISBN: 978-3-9816508-8-4.
  19. M. Würl, F. Englbrecht, J. Hauffe, K. Parodi, M. Hillbrand, Dose output dependence on field size and spot spacing in scanned proton therapy – a comparison of measurements with TPS and MC calculations, DGMP Marburg 2015, Abstractband p. 338, ISBN: 978-3-9816508-8-4.
  20. J. Bauer, C. Kurz, W. Chen, T. Tessonnier, J. Liebl, T. Haberer, K. Herfarth, J. Debus, K. Parodi, PET/CT-basierte Therapieverifikation am Heidelberger Ionenstrahl-Therapiezentrum, DGMP Marburg 2015, Abstractband p. 470-471, ISBN: 978-3-9816508-8-4.
  21. J. Hoppmann, J. Bin, C. Gianoli, W. Ma, C. Kreuzer, J. Schreiber, K. Parodi, G. Dedes, Angular-energy distribution reconstruction of electrons emitted from laser irradiated foils, DGMP Marburg 2015, Abstractband p. 484-485, ISBN: 978-3-9816508-8-4.
  22. T. Tessonnier, A. Mairani, S. Brons, T. Haberer, J. Debus and K. Parodi, 2015, Experimental dosimetric comparisons at heidelberg ion beam therapy center of 1H, 4He, 12C and 16O ion beams, Physica Medica: European Journal of Medical Physics 31, e26-7.

Nuclear Physics

  1. B. Seiferle, L. v.d. Wense, and P.G. Thirolf,  A VUV detection system for the direct identification of the fluorescence radiation of 229mTh, Verhandl. DPG (VI) 50, HK 6.2 (2015).
  2. L. v.d. Wense, B. Seiferle, M. Laatiaoui, P.G. Thirolf, Preparations for an optical access to the lowest nuclear excitation in 229Th, Verhandl. DPG (VI) 50, HK 66.3 (2015).
  3. C. Droese, K. Blaum, M. Block, P. Chhetri, S. Eliseev, F. Herfurth, M. Laatiaoui, F. Lautenschläger, E. Minaya Ramirez, L. Schweikhard, and P. Thirolf, Performance of the Cryogenic Buffer-Gas Stopping Cell at SHIPTRAP, Verhandl. DPG (VI) 50, MS 2.6 (2015).
  4. C. Weber and P.G. Thirolf, An ion trap for in-trap nuclear decay-spectroscopy experiments, Verhandl. DPG (VI) 50, MS 6.9 (2015).


Thesis Works:


  1. J. Bin, Laser-Driven Ion Acceleration From Carbon Nano-Targets With Ti:Sa Laser Systems
  2. C. Lang, Design of a Compton camera for medical imaging and characterization of its components

Master Thesis (internal):

  1. B. Seiferle, Setup for a VUV detection system for the direct identification of the fluorescence radiation of 229mTh
  2. K. Kröninger, Implementation of an analytical PET range verification tool for proton therapy in the TPS RayStation
  3. S. Schmid, Systematic Monte Carlo Study on in vivo proton range verification with prompt gamma photons in proton therapy
  4. J. Hoppmann, Monte Carlo simulation of a Wide Angle Spectrometer and reconstruction of the angular-energy distribution of electrons emitted from laser irradiated foils
  5. N. Hudobivnik, DECT based Proton Therapy Treatment Planning for Head and Neck
  6. S. Meyer, A systematic Monte Carlo study of the influence of different acquisition and detector parameters on the image quality of carbon ion radiography and tomography using a range telescope
  7.  T. Marinsek, Deriving spatial information from a monolithic LaBr3 scintillator
  8. F. Lindner, Online diagnostics for laser accelerated ions and electrons
  9. T. Rösch, A permanent magnet focusing structure for laser-accelerated ions
  10. A. Resch: Development of a Monte Carlo simulation-based treatment planning tool for proton therapy

Master Thesis (external):

  1. L. Bienert, Messung optischer Gewebeparameter: Optimierung und Vergleich verschiedener Messmethoden (LFL Klinikum Großhadern)
  2. M. Hoesl, In-vivo range verification in proton particle theapy - applied and verified on the example o prostate cancer in an anthropomorphic phantom (Massachusetts General Hospital) 
  3. P. Schaur, Grundlegende Untersuchungen zur Optimierung der laser-gestützten endoluminalen Behandlung bei Varikosis (LFL Klinikum Großhadern)
  4. L. Vomacka, Automated image segmentation of dynamic PET and SPECT data with clustering methods (LMU Klinikum Großhadern)
  5. A. Gosewisch, Dosimetrie in der 177Lu-Radionuklid Therapie unter Verwendung von Monte Carlo Simlationen (LMU Klinikum Großhadern)

Bachelor Thesis (internal):

  1. D. Kleinmaier, Adapting prompt gamma range verification tools to proton therapy of head and neck cancer
  2. A. Mayr, Quality Assurance in Radiotherapy with the RadEye pixel detector system
  3. M. Rädler, Analyse des zeitlichen Verlaufs für adaptive Strahlentherapie für Krebserkrankungen im Kopf- und Halsbereich


Bachelor Thesis (external):

  1. M. Aichmüller, Implementation of a coregistration-algorithm fo 3D images of different sampling in order to analyse dynamic PET images (LMU Klinikum Großhadern)
  2. I. Manakov, Implementierung einer voxel-weisen pharmakokinetischen Modellierung von dynamischen PET-Aufnahmen (LMU Klinikum Großhadern)
  3. J. Rudrof, Quantitative Auswertung von Fluoreszenzmessungen bei der  IPDT von Glioblastomen (LFL Klinikum Großhadern)
  4. K. Dinkel, Untersuchung verschiedener Möglichkeiten zur Berücksichtigung des Bestrahlungstisches in der Bestrahlungsplanung und der Planverifikation mit dem Phantom Octavius4D (Klinikum Großhadern)
  5. L. Grimmeißen, Comparison of measured and by different Asgorithms calculated dose in inhomogeneous mediums (LMU Klinikum Großhadern)